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  1. Primary cystic neoplasms of the peritoneum are rare lesions and not commonly encountered in practice. Many intra-abdominal processes may mimic cystic masses within the peritoneal cavity and pose a diagnostic c...

    Authors: Savita S. Patil, Parth B. Shah, Jyoti K. Kudrimoti and Leena A. Nakate
    Citation: Surgical and Experimental Pathology 2021 4:17
  2. Malignant Solitary fibrous tumour (SFT) is an uncommon mesenchymal tumour with aggressive clinical behaviour as compared to its benign counterpart. There are only a handful of reports of extra-pleural malignan...

    Authors: Arshi Beg, Jeenal Parikh, Amit Janu and Rajiv Kumar Kaushal
    Citation: Surgical and Experimental Pathology 2021 4:16
  3. Adoption of molecular pathology in Brazil is currently very limited. Of note, there are no programs for training new molecular pathologists in the country; thus, documents compiling nationally applicable infor...

    Authors: Isabela Werneck da Cunha, Renata de Almeida Coudry, Mariana Petaccia de Macedo, Emilio Augusto Campos Pereira de Assis, Stephen Stefani and Fernando Augusto Soares
    Citation: Surgical and Experimental Pathology 2021 4:15

    The Correction to this article has been published in Surgical and Experimental Pathology 2021 4:18

  4. TGFβ signaling exerts context-specific effects in breast cancer (BC) pathogenesis and single nucleotide polymorphisms (SNPs) in TGFβ-signaling components play a role in the genetic control of their expression ...

    Authors: Glauco Akelinghton Freire Vitiello, Marla Karine Amarante, Jefferson Crespigio, Bruna Karina Banin Hirata, Nathalia de Sousa Pereira, Karen Brajão de Oliveira, Roberta Losi Guembarovski and Maria Angelica Ehara Watanabe
    Citation: Surgical and Experimental Pathology 2021 4:14
  5. Lymphangioleiomyomatosis (LAM) is a rare neoplastic disease of the lung with a characteristic feature of diffuse cystic changes in bilateral lungs. Lung transplantation is considered to be one of the effective...

    Authors: Sakda Sathirareuangchai, Jenny L. Weon, Suzanne Tintle, Kiran Batra, Shirley X. Yan and Jose R. Torrealba
    Citation: Surgical and Experimental Pathology 2021 4:13
  6. SARS CoV-19 was declared as a pandemic by the World Health Organization (WHO), raising up challenges on various levels ranging from therapeutics to diagnostics. The conventional autopsy technique may pose a he...

    Authors: Ajay H. Bhandarwar, Girish D. Bakhshi, Eham Arora, Nikhil Dhimole, Sanjay R. Bijwe, Shubhangi V. Agale, Megha S. Kinake, Shilpa Domkundwar and Yogesh Thube
    Citation: Surgical and Experimental Pathology 2021 4:12
  7. Parkin, a protein encoded by PRKN, discovered in the context of Parkinson’s disease, controls proteasomal degradation by protein ubiquitination and acts on cell cycle control and mitochondrial homeostasis, among ...

    Authors: Eduardo Morais de Castro, Leonardo Vinícius Barbosa, João Vitor Alves Ferreira, Diancarlos Pereira de Andrade, Rosiane Guetter Mello, Luiz Fernando Bleggi Torres, Lucia de Noronha and Cleber Machado-Souza
    Citation: Surgical and Experimental Pathology 2021 4:11
  8. Triple-negative breast cancer (TNBC) is a heterogeneous disease that represents 10–20% of breast cancer cases. The prognosis for advanced TNBC is usually poor, with a median overall survival of approximately 1...

    Authors: Kátia Ramos Moreira Leite, Carlos Henrique Barrios, Antônio Carlos Buzaid, Débora Gagliato, Helenice Gobbi and Fernando Soares
    Citation: Surgical and Experimental Pathology 2021 4:10
  9. Karyomegalic interstitial nephritis (KIN) is an uncommon cause of chronic interstitial nephritis that eventually progresses to end-stage renal disease. Overall less than 50 cases have been reported in the lite...

    Authors: Monica Sivakumar, Balan Louis Gaspar and Balakrishnan Narasimhan
    Citation: Surgical and Experimental Pathology 2021 4:8
  10. Extracellular matrix (ECM) represents more than a mere intercellular cement. It is physiologically active in cell communication, adhesion and proliferation. Collagen is the most abundant protein, making up to ...

    Authors: Rodrigo de Andrade Natal, Javier Adur, Carlos Lenz Cesar and José Vassallo
    Citation: Surgical and Experimental Pathology 2021 4:7
  11. A solitary fibrous tumor (SFT) is an uncommon neoplasm of mesenchymal and probably fibroblastic origin, occurring mainly in the extremities, and pleura. However, a primary involvement of endocrine organs is ra...

    Authors: S. E. Huisman, I. Verlinden, P. van Battum and J. W. A. Leijtens
    Citation: Surgical and Experimental Pathology 2021 4:6
  12. Adenomatoid tumors (AT) are benign neoplasms of mesothelial origin that occur more frequently in the genital tracts. In uterus, AT are usually located in the subserosa of the cornual myometrium. Microscopicall...

    Authors: Flora Ávila Adorno, Karina Munhoz de Paula Alves Coelho, Giuliano Stefanello Bublitz, Jaqueline Stall and Paulo Henrique Condeixa de França
    Citation: Surgical and Experimental Pathology 2021 4:5
  13. Classification of renal cell carcinomas has become more challenging. The 2016 WHO classification included 14 different subtypes and 4 emerging/provisional entities, and recent literature indicates new entities...

    Authors: Daniel Abensur Athanazio, Luciana Schultz Amorim, Isabela Werneck da Cunha, Katia Ramos Moreira Leite, Alexandre Rolim da Paz, Regina de Paula Xavier Gomes, Fabio Rocha Fernandes Tavora, Sheila Friedrich Faraj, Marcela Santos Cavalcanti and Stephania Martins Bezerra
    Citation: Surgical and Experimental Pathology 2021 4:4
  14. Muscle biopsies are important diagnostic procedures in neuromuscular practice. Recent advances in genetic analysis have profoundly modified Myopathology diagnosis.

    Authors: Ana Cotta, Elmano Carvalho, Antonio Lopes da-Cunha-Júnior, Jaquelin Valicek, Monica M. Navarro, Sidney Baptista Junior, Eni Braga da Silveira, Maria Isabel Lima, Bruno Arrivabene Cordeiro, Alexandre Faleiros Cauhi, Miriam Melo Menezes, Simone Vilela Nunes, Antonio Pedro Vargas, Rafael Xavier Neto and Julia Filardi Paim
    Citation: Surgical and Experimental Pathology 2021 4:3
  15. Complete lymph node dissection (CLND) following a positive sentinel lymph node biopsy (SLNB) has been the standard treatment for years. However, there is increasing evidence that CLND could be omitted. Approxi...

    Authors: Maribel L. Da Cunha Cosme, Juan F. Liuzzi Samaterra, Saul A. Siso Cardenas and José I. Chaviano Hernández
    Citation: Surgical and Experimental Pathology 2021 4:2
  16. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Mitul B. Modi, Ata S. Moshiri, Toru Shoji, Martin C. Mihm Jr, Xiaowei Xu and David E. Elder
    Citation: Surgical and Experimental Pathology 2021 4:1

    The original article was published in Surgical and Experimental Pathology 2020 3:16

  17. The IgG4-related disease (IgG4-RD) is a systemic immune-mediated non-neoplastic disease associated with IgG4 positive plasma cells and fibrosis that often presents as a mass lesion. Although the disease could ...

    Authors: Balan Louis Gaspar
    Citation: Surgical and Experimental Pathology 2020 3:30
  18. Breast cancer is a major public health problem worldwide. It is recommended that small breast lesions or those suspicious for malignancy be evaluated via histopathological examination (“core biopsy” or surgica...

    Authors: Jessica Aline Tomelin de Cursi, Mariângela Esther Alencar Marques, Cristina Andrea Campos de Assis Cunha Castro, Fernando Carlos Schmitt and Cleverson Teixeira Soares
    Citation: Surgical and Experimental Pathology 2020 3:29
  19. Blastocyst implantation and neoplastic invasion have some common properties related to tissue invasion, mediated by various cytokines.

    Authors: Luciana Pietro, Fátima Bottcher-Luiz, Lício Augusto Velloso, Joseane Morari, Marcelo Nomura and Liliana A. Lucci De Angelo Andrade
    Citation: Surgical and Experimental Pathology 2020 3:28
  20. Prostate adenocarcinoma has well known benign mimickers. Histiocytic proliferations usually impose differential diagnosis with high-grade component of acinar adenocarcinoma (Gleason pattern 5).

    Authors: Maiara Ferreira de Souza, Diogo Diniz de Moraes, Talita Porto da Costa, Juarez Araújo Andrade, Huarne João José Tenório de Macêdo, Augusto Paraíso and Daniel Abensur Athanazio
    Citation: Surgical and Experimental Pathology 2020 3:26
  21. Urothelial carcinoma shows wide plasticity and broad morphologic spectrum. In many instances, the presence of papillary morphology is reassuring of the urothelial histogenesis of a high-grade invasive lesion b...

    Authors: Daniel Abensur Athanazio, Maiara Ferreira de Souza and Maria Estela Pompeu do Amaral
    Citation: Surgical and Experimental Pathology 2020 3:25
  22. Lupus mastitis (LM) is a rare complication of systemic lupus erythematosus (SLE) or discoid lupus erythematosus (DLE). The clinical presentations of LM may mimic breast malignancy, and biopsy or excision is us...

    Authors: Mingfei Yan, Philip Bomeisl, Hannah Gilmore, Kwadwo Oduro and Aparna Harbhajanka
    Citation: Surgical and Experimental Pathology 2020 3:24
  23. Rosai-Dorfman disease (RDD) is a rare but well-defined, histiocytic proliferative disorder with massive lymphadenopathy.

    Authors: Mohammad Hossein Anbardar, Samaneh Hamzehloo, Fatemeh Fazeli, Soheila Zareifar, Mohammad Hadi Imanieh, Mohammadhossein Bahmanzadegan Jahromi and Amir Mohammad Ghorbani
    Citation: Surgical and Experimental Pathology 2020 3:27
  24. Cystic neutrophilic granulomatous mastitis (CNGM) is an uncommon and recently described pattern of granulomatous mastitis. To our knowledge, no cases have been described during chemotherapy for invasive breast...

    Authors: Juliana Ribeiro de Freitas, Maiara Ferreira de Souza, Mayana Lopes, Larissa Bitencourt and Daniel Abensur Athanazio
    Citation: Surgical and Experimental Pathology 2020 3:23
  25. The term low-grade oncocytic tumour of kidney is an emerging entity describing CD117-negative and cytokeratin 7-positive indolent tumors with overlapping morphological features between oncocytic tumors.

    Authors: Cláudio Galeno Ramalho de Andrade Melo, Marcus Vinicius Nunes Xavier, Isabela Soares Pimenta and Daniel Abensur Athanazio
    Citation: Surgical and Experimental Pathology 2020 3:22
  26. Adenoid cystic carcinoma and primary squamous cell carcinoma are both rare breast neoplasms, which possess drastically different morphological and molecular features as well as distinguishing clinical behavior...

    Authors: Mingfei Yan, Phillip Bomeisl, Hannah Gilmore and Aparna Harbhajanka
    Citation: Surgical and Experimental Pathology 2020 3:20
  27. Recurrent disease following failed chemotherapy for muscle-invasive urothelial carcinoma (UC) has no universally accepted treatment guidelines. Receptors for luteinizing hormone-releasing hormone (LHRHR) have ...

    Authors: Saba Yasir, Gustavo Fernandez-Castro, Numra Aslam Bajwa, Norman Block, Andrew Schally, Richard Cote and Merce Jorda
    Citation: Surgical and Experimental Pathology 2020 3:19
  28. Coronavirus disease 2019 (COVID-19), which started in Wuhan, China, in late December 2019, was declared a pandemic, infecting more than twelve million people worldwide. Few studies have reported the findings o...

    Authors: Elif Usturalı Keskin, Ebru Tastekin, Nuray Can, İnci Usta, Nermin Tuncbilek, Derya Karabulut, Osman Kula and Onur Kırkızlar
    Citation: Surgical and Experimental Pathology 2020 3:21
  29. The World Health Organization’s (WHO) update of 2017 defines the cut-off for BCL2 in immunohistochemistry (IHC) in 50% of stained cells in diffuse large B-cell lymphomas (DLBCL). The WHO’s 2017 classification,...

    Authors: Cristiano Claudino Oliveira, Maria Aparecida Custódio Domingues, Isabela Werneck da Cunha and Fernando Augusto Soares
    Citation: Surgical and Experimental Pathology 2020 3:18
  30. The Notch signaling pathway and its modulators are directly related to growth, verticalization and metastasis in melanoma, being a possible therapeutic target for the treatment of this type of cancer. There ar...

    Authors: Lorena Dal Collina Sangiuliano, Renato Santos de Oliveira Filho, Daniel Arcuschin de Oliveira, Heitor Carvalho Gomes and Lydia Masako Ferreira
    Citation: Surgical and Experimental Pathology 2020 3:17
  31. Eccrine porocarcinoma is a rare malignancy accounting for 0.005 to 0.01% of all cutaneous tumors. However, its etiology is not well established. Herein we are reporting the occurrence of metastatic porocarcino...

    Authors: Mitul B. Modi, Ata S. Moshiri, Toru Shoji, Martin C. Mihm Jr, Xiaowei Xu and David E. Elder
    Citation: Surgical and Experimental Pathology 2020 3:16

    The Correction to this article has been published in Surgical and Experimental Pathology 2021 4:1

  32. To evaluate the frequency of divergent differentiations / variant morphology in urothelial carcinoma, and their association with muscle-invasive disease at diagnosis.

    Authors: Suelen Cunha Santana, Maiara Ferreira de Souza, Maria Estela Pompeu Amaral and Daniel Abensur Athanazio
    Citation: Surgical and Experimental Pathology 2020 3:14
  33. Morphologic distinction between uterine leiomyosarcoma (ULMS) and endometrial stromal sarcoma (ESS) alone is not straightforward and has been shown to be challenging especially with poor differentiation, so im...

    Authors: Mohamed Ali Alabiad, Ola A. Harb, Mustafa Taha Abdelfattah, Basant Sh. El-Shafaay, Ahmed K. El-Taher and Elsayed I. El-Hendawy
    Citation: Surgical and Experimental Pathology 2020 3:13
  34. Benign melanocytic lesions of the prostate are rare and classified as blue nevus or melanosis. Both lesions have about 30 cases each reported in English literature.

    Authors: Maria Estela Pompeu do Amaral and Daniel Abensur Athanazio
    Citation: Surgical and Experimental Pathology 2020 3:12
  35. Meckel Gruber Syndrome (MKS) is a rare autosomal recessive malformation syndrome characterized by multiple congenital anomalies ultimately leading to the death of fetus in utero or shortly after birth. It is c...

    Authors: Marquess Raj, Sujata Dhanuka, Prerna Agarwal, Suresh Lakki Reddy and Sethuramalingam Vivekananthan
    Citation: Surgical and Experimental Pathology 2020 3:11
  36. Rhabdomyosarcomas with areas reminiscent of adult type rhabdomyoma are rare and almost exclusive of pretreated tumors. We present a case of 17-year-old patient who sought medical assistance due to a right pain...

    Authors: Suelen Cunha Santana, Filip Messias Santana Prado, Marcos Lima de Oliveira Leal, Paulo Athanazio and Daniel Abensur Athanazio
    Citation: Surgical and Experimental Pathology 2020 3:10
  37. Angiogenesis is one of the hallmarks of cancer. This complex mechanism of tumor progression provides tumors cells with essential nutrients. There have been a limited number of investigations of markers of angi...

    Authors: Luiz Victor Maia Loureiro, Luciano Neder, Donato Callegaro-Filho, Ludmila de Oliveira Koch, João Norberto Stavale and Suzana Maria Fleury Malheiros
    Citation: Surgical and Experimental Pathology 2020 3:9
  38. Gene mutations correlated with histological and immunohistochemical phenotypes of hepatocellular adenoma were recently identified. Based on these findings, four adenoma subtypes were distinguished. We classify...

    Authors: Carla Henriques Agostini, Osmar Damasceno Ribeiro, Arlete Fernandes, Adriana Caroli-Bottino and Vera Lucia Pannain
    Citation: Surgical and Experimental Pathology 2020 3:8
  39. Local control for the treatment of primary bone tumors is generally delayed following neoadjuvant chemotherapy. This was born out of the historical need to manufacture custom implants when performing limb-salv...

    Authors: Yoav S. Zvi, Amit Singla, Alexander J. Chou, Janet Tingling, Rui Yang, Bang H. Hoang and David S. Geller
    Citation: Surgical and Experimental Pathology 2020 3:5
  40. The accurate graduation of a phyllodes tumor (PT) is critical for effective treatment as it allows correct surgical management, and avoids inadequate excision for malignant or borderline PT, or surgical overtr...

    Authors: L. F. Rivero, M. S. Graudenz, P. Aschton-Prolla, A. M. Delgado and L. M. Kliemann
    Citation: Surgical and Experimental Pathology 2020 3:7
  41. Elastic fibers deposition is triggered during liver fibrosis and is related to worse clinical prognosis in chronic hepatitis C patients. This study aimed to verify if a new method for elastic fiber quantificat...

    Authors: Carine Leite, Rodrigo Tzovenos Starosta, Eduardo Neubarth Trindade, Manoel Roberto Maciel Trindade, Mário Reis Álvares-da-Silva and Carlos Thadeu Schmidt Cerski
    Citation: Surgical and Experimental Pathology 2020 3:4
  42. Mucinous cystic neoplasms (MCNs) of pancreas are relatively rare, occur almost exclusively in middle-aged females, and are overwhelmingly located in the body and tail of the pancreas, histologically show an ov...

    Authors: Nasir Ud Din, Maha Zubair, Jamshid Abdul-Ghafar and Zubair Ahmad
    Citation: Surgical and Experimental Pathology 2020 3:6
  43. Penile squamous cell carcinoma (PSSC) has some non-HPV associated precursos and lichen planus is not considered one of them.

    Authors: Marcos Lima de Oliveira Leal, Lucas Rosemberg Pellegrino Jorge Alencar, Suelen Cunha Santana, Bianca Carla Azevedo de Souza and Daniel Abensur Athanazio
    Citation: Surgical and Experimental Pathology 2020 3:1

    The Correction to this article has been published in Surgical and Experimental Pathology 2022 5:15

  44. The use of a circular stapling device to create an anastomosis following colonic or rectal resection is common practice in the United Kingdom. Histopathological analysis of the anastomotic doughnuts produced t...

    Authors: Steven Dixon, Hannah Barrow and Jane Hughes
    Citation: Surgical and Experimental Pathology 2020 3:2
  45. Despite the immunotherapeutics and target therapy agents, the survival of patients with advanced melanoma is still low. Notch signaling is able to regulate many aspects of melanomagenesis. Comparative analyses...

    Authors: Renato Santos de Oliveira Filho, Alexandre Lavorato Soares, Francisco Macedo Paschoal, Gisele Gargantini Rezze, Ebe Oliveira, Ricardo Macarenco, Antonio Carlos Buzaid and Lydia Masako Ferreira
    Citation: Surgical and Experimental Pathology 2019 2:27
  46. Leprosy is a major public health concern in many developing countries. Mycobacterium leprae (M. leprae), the causative agent of leprosy, has the ability to parasitize different types of human cells and tissues. I...

    Authors: Cleverson Soares Teixeira, Patricia Pinheiro Montalvão, Isabella Tostes de Oliveira and Patrick Alexander Wachholz
    Citation: Surgical and Experimental Pathology 2019 2:26
  47. Gastrointestinal Stromal Tumors (GIST) present different types of mutations that may or may not be sensitive to specific target therapy. The laboratory procedure required to prepare histological sections tradi...

    Authors: Denise Barcelos, Karina Funabashi, Susana Mazloum, Mariana Fernandes and Leonardo Cardili
    Citation: Surgical and Experimental Pathology 2019 2:25

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