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  1. Immunofluorescence studies on frozen sections are an essential component in the evaluation of renal biopsies. The basic panel in most centres constitutes IgG, IgA, IgM, C3c, C1q, Kappa and Lambda light chain a...

    Authors: Shilpi Thakur and Balan Louis Gaspar
    Citation: Surgical and Experimental Pathology 2023 6:6
  2. Pulmonary hemosiderosis is a rare disease that may be idiopathic or have a secondary etiology, such as mitral stenosis. The disease is a clinical and functional consequence of iron overload in the lungs in the...

    Authors: Jadson Soares Laudelino, Fernando Moreira Batista Aguiar, Filadélfia Passos Rodrigues Martins, Rosineli Leopoldino de Oliveira, Glauberto Rolim Cartaxo Bezerra Cruz and Aline Lobo Ramos
    Citation: Surgical and Experimental Pathology 2023 6:5
  3. CDX2, a homeobox gene is the marker of intestinal differentiation. Its expression may lead to misdiagnosis while evaluating metastasis from unknown primary. In the present narrative, we discuss the clinical, m...

    Authors: Krachi Agarwal, Preeti Agarwal, Shipra Singh, Mili Jain and Sumaira Qayoom
    Citation: Surgical and Experimental Pathology 2023 6:4
  4. Extraskeletal osteosarcoma arising in the penis is exceedingly rare and its major differential diagnosis is sarcomatoid carcinoma.

    Authors: Daniel Abensur Athanazio, Maurício Bessa, José do Egypto Pereira Filho and Paulo Roberto Fontes Athanazio
    Citation: Surgical and Experimental Pathology 2023 6:3
  5. Renal cell carcinoma, notably clear cell renal cell carcinoma in particular, show remarkable predisposition for intravenous growth. Retrograde venous invasion results in intravascular emboli in renal sinus and...

    Authors: Daniel Abensur Athanazio, Maiara Ferreira de Souza and Maria Estela Pompeu do Amaral
    Citation: Surgical and Experimental Pathology 2023 6:2
  6. The cytokines play an essential role in acute inflammatory processes, and the IL-17 may be responsible for ambiguous aspects, and the correlation with genetic polymorphisms could improve the search for this cr...

    Authors: Vanessa Yumie Salomão Watanabe Liberalesso, Marina Luise Viola Azevedo, Mineia Alessandra Scaranello Malaquias, Caroline Busatta Vaz de Paula, Seigo Nagashima, Daiane Gavlik de Souza, Plínio Cézar Neto, Kauana Oliveira Gouveia, Larissa Cristina Biscaro, Ana Luisa Garcia Giamberardino, Gabrielle Tasso Gonçalves, Thais Teles Soares Kondo, Sonia Maria Raboni, Isabelle Weiss, Cleber Machado-Souza and Lucia de Noronha
    Citation: Surgical and Experimental Pathology 2023 6:1
  7. Paget’s disease of the nipple (PDN) is a rare type of cancer of the nipple-areola complex. We examined GATA3 protein expression in PDN to determine its potential value as an adjunct marker in the differential ...

    Authors: Tércia Jovino Neves Santos, Marina De Brot, Stephania Martins Bezerra, Samuel Rodrigues Buniatti, Victor Piana de Andrade, Fernando Augusto Soares, João Víctor Alves de Castro and Cynthia Aparecida Bueno de Toledo Osório
    Citation: Surgical and Experimental Pathology 2022 5:23
  8. A hypertrophic / vegetating variant of Darier disease causing massive verruciform genital tumors is exceedingly rare.

    Authors: Caroline Passos Cardoso, Herbert Ives Barretto Almeida, Nilma Antas Neves, Fabiola Leal and Daniel Abensur Athanazio
    Citation: Surgical and Experimental Pathology 2022 5:22
  9. BCG is the standard of care to treat high risk non-muscle invasive bladder cancer (NMIBC), reducing recurrence. PD-L1 is a ligand of the co-inhibitory receptor PD1 that has been shown to be expressed by tumor ...

    Authors: Katia R. M. Leite, Denis Reis Morais, Cristina Massoco, Sabrina T. Reis, Nayara I. Viana, Iran A. Silva, Vanessa Guimaraes, Ruan Pimenta, Gabriel Arantes, Miguel Srougi and Willian Carlos Nahas
    Citation: Surgical and Experimental Pathology 2022 5:21
  10. Timely and correct assessment of histopathological, immunohistochemical and molecular features of biopsy and surgical specimens is of paramount importance in the provision of care to patients with breast cance...

    Authors: Helenice Gobbi, Filomena Marino Carvalho, Rosemar Macedo Sousa Rahal, Maria Ines Klôh and Dimitrius Leonardo Pitol
    Citation: Surgical and Experimental Pathology 2022 5:20
  11. This study was designed to evaluate the frequency of developing second and subsequent primary cancers among cancer survivors.

    Authors: Anjali Sharma, Ajay Sharma, Sanjeev Patni, Anil Gupta, Naresh Ledwani, Shashikant Saini, Nidhi Patni, Ajay Bapna, Naresh Somani, Mudit Sharma, Shubham Verma, Gulshan Kumar Sharma and Vandana Nunia
    Citation: Surgical and Experimental Pathology 2022 5:19
  12. Lymphovascular invasion is a hallmark of malignant neoplasms, however the presence of benign epithelium within vessels has been reported in benign processes, albeit infrequently. The proposed mechanism to expl...

    Authors: Quinn Miller, Nishi Dave, Nikolay Popnikolov, Sidney D. Bruce and Hector Mesa
    Citation: Surgical and Experimental Pathology 2022 5:18
  13. Intracellular Ca2+ levels can modulate several cellular functions, including proliferation and other processes found altered in neoplastic cells. Helping to maintain Ca2+ homeostasis, L-type voltage-dependent Ca2...

    Authors: Flávia Aguiar, Paula Rhana, Enrrico Bloise, Andreia Laura Prates Rodrigues and Enio Ferreira
    Citation: Surgical and Experimental Pathology 2022 5:16
  14. A collision tumor is a neoplastic lesion comprised of two or more distinct cell populations with distinct borders. Desmoid fibromatosis (DF) is a rare musculoaponeurotic tissue tumor that grows deep in the con...

    Authors: Lorenzo Gitto, Thomas Vandermeer, David J. Lubin and Daniel J. Zaccarini
    Citation: Surgical and Experimental Pathology 2022 5:13
  15. The emergence of digital pathology environments and the application of computer vision to the analysis of histological sections has given rise to a new area of Anatomical Pathology, termed Computational Pathol...

    Authors: Washington L. C. dos-Santos, Luiz A. R. de Freitas, Angelo A. Duarte, Michele F. Angelo and Luciano R. Oliveira
    Citation: Surgical and Experimental Pathology 2022 5:10
  16. Advances in digital imaging in pathology and the new capacity to scan high-quality images have change the way to practice and research in surgical pathology. QuPath is an open-source pathology software that of...

    Authors: Aline Rodrigues, Cleto Nogueira, Laura Cardoso Marinho, Guilherme Velozo, Juliana Sousa, Paulo Goberlanio Silva and Fabio Tavora
    Citation: Surgical and Experimental Pathology 2022 5:12
  17. This study evaluated histopathological characteristics of bone marrow (BM) of patients with immune thrombocytopenic purpura (ITP) and sought to find possible associations among them and clinical aspects.

    Authors: Rafael Guimarães Kanda, Lígia Niero-Melo, Maria Aparecida Custódio Domingues and Cristiano Claudino Oliveira
    Citation: Surgical and Experimental Pathology 2022 5:9
  18. Small cell-like change in prostatic neoplasia (both invasive adenocarcinoma and intraepithelial lesions) is described in three previous reports. None of them to date proved to be associated with overt prostate...

    Authors: Daniel Abensur Athanazio and Maiara Ferreira de Souza
    Citation: Surgical and Experimental Pathology 2022 5:6
  19. Meningiomas represent the most frequently diagnosed intracranial tumors. Inflammatory cells present in the tumor can modulate both antitumor and protumor functions, and modify the therapeutic response. Hematol...

    Authors: Camila Batista de Oliveira Silva, Bruna Araújo, Bárbara Roberta Ongaratti, Tainá Mafalda dos Santos, Carolina Garcia Soares Leães Rech, Lígia Barbosa Coutinho, Nelson Pires Ferreira, Miriam da Costa Oliveira and Julia Fernanda Semmelmann Pereira-Lima
    Citation: Surgical and Experimental Pathology 2022 5:5
  20. The inverted (hobnail) variant of high-grade prostatic intraepithelial neoplasia (HGPIN) has been reported in two previous series and one case of inverted polarity in invasive adenocarcinoma has been reported....

    Authors: Daniel Abensur Athanazio, Maiara Ferreira de Souza and Maria Estela Pompeu do Amaral
    Citation: Surgical and Experimental Pathology 2022 5:3
  21. Intramedullary lipomatous tumors are rare and mostly reported in the metaphysis of the femur, tibia, and fibula. Myelolipomas are very rare tumors composed of adipose tissue and hematopoietic cells commonly re...

    Authors: Anoshia Afzal, Sepideh N. Asadbeigi, Maria Kamal, Lewis Hassell and Kar-Ming Fung
    Citation: Surgical and Experimental Pathology 2022 5:2
  22. Cribrifrom-morular variant of papillary thyroid carcinoma (CMVPTC) is an uncommon thyroid neoplasm that occurs predominantly in women and is sometime associated with familial adenomatous polyposis (FAP). Some ...

    Authors: Kusum L. Sharma, Ravi B. Singh, Nisreen Fidda and Ricardo V. Lloyd
    Citation: Surgical and Experimental Pathology 2022 5:1
  23. Although usually believed to be harmless, intestinal spirochetosis may active erosive colitis associated with intestinal spirochetosis that may mimic idiopathic chronic inflammatory bowel disease. Case present...

    Authors: Fabio Dantas de Paula, Glicia Estevam de Abreu, Maiara Ferreira de Souza, Luiz Antonio Rodrigues de Freitas and Daniel Abensur Athanazio
    Citation: Surgical and Experimental Pathology 2021 4:19
  24. Primary cystic neoplasms of the peritoneum are rare lesions and not commonly encountered in practice. Many intra-abdominal processes may mimic cystic masses within the peritoneal cavity and pose a diagnostic c...

    Authors: Savita S. Patil, Parth B. Shah, Jyoti K. Kudrimoti and Leena A. Nakate
    Citation: Surgical and Experimental Pathology 2021 4:17
  25. Malignant Solitary fibrous tumour (SFT) is an uncommon mesenchymal tumour with aggressive clinical behaviour as compared to its benign counterpart. There are only a handful of reports of extra-pleural malignan...

    Authors: Arshi Beg, Jeenal Parikh, Amit Janu and Rajiv Kumar Kaushal
    Citation: Surgical and Experimental Pathology 2021 4:16
  26. Adoption of molecular pathology in Brazil is currently very limited. Of note, there are no programs for training new molecular pathologists in the country; thus, documents compiling nationally applicable infor...

    Authors: Isabela Werneck da Cunha, Renata de Almeida Coudry, Mariana Petaccia de Macedo, Emilio Augusto Campos Pereira de Assis, Stephen Stefani and Fernando Augusto Soares
    Citation: Surgical and Experimental Pathology 2021 4:15

    The Correction to this article has been published in Surgical and Experimental Pathology 2021 4:18

  27. TGFβ signaling exerts context-specific effects in breast cancer (BC) pathogenesis and single nucleotide polymorphisms (SNPs) in TGFβ-signaling components play a role in the genetic control of their expression ...

    Authors: Glauco Akelinghton Freire Vitiello, Marla Karine Amarante, Jefferson Crespigio, Bruna Karina Banin Hirata, Nathalia de Sousa Pereira, Karen Brajão de Oliveira, Roberta Losi Guembarovski and Maria Angelica Ehara Watanabe
    Citation: Surgical and Experimental Pathology 2021 4:14
  28. Lymphangioleiomyomatosis (LAM) is a rare neoplastic disease of the lung with a characteristic feature of diffuse cystic changes in bilateral lungs. Lung transplantation is considered to be one of the effective...

    Authors: Sakda Sathirareuangchai, Jenny L. Weon, Suzanne Tintle, Kiran Batra, Shirley X. Yan and Jose R. Torrealba
    Citation: Surgical and Experimental Pathology 2021 4:13
  29. SARS CoV-19 was declared as a pandemic by the World Health Organization (WHO), raising up challenges on various levels ranging from therapeutics to diagnostics. The conventional autopsy technique may pose a he...

    Authors: Ajay H. Bhandarwar, Girish D. Bakhshi, Eham Arora, Nikhil Dhimole, Sanjay R. Bijwe, Shubhangi V. Agale, Megha S. Kinake, Shilpa Domkundwar and Yogesh Thube
    Citation: Surgical and Experimental Pathology 2021 4:12
  30. Parkin, a protein encoded by PRKN, discovered in the context of Parkinson’s disease, controls proteasomal degradation by protein ubiquitination and acts on cell cycle control and mitochondrial homeostasis, among ...

    Authors: Eduardo Morais de Castro, Leonardo Vinícius Barbosa, João Vitor Alves Ferreira, Diancarlos Pereira de Andrade, Rosiane Guetter Mello, Luiz Fernando Bleggi Torres, Lucia de Noronha and Cleber Machado-Souza
    Citation: Surgical and Experimental Pathology 2021 4:11
  31. Triple-negative breast cancer (TNBC) is a heterogeneous disease that represents 10–20% of breast cancer cases. The prognosis for advanced TNBC is usually poor, with a median overall survival of approximately 1...

    Authors: Kátia Ramos Moreira Leite, Carlos Henrique Barrios, Antônio Carlos Buzaid, Débora Gagliato, Helenice Gobbi and Fernando Soares
    Citation: Surgical and Experimental Pathology 2021 4:10
  32. Karyomegalic interstitial nephritis (KIN) is an uncommon cause of chronic interstitial nephritis that eventually progresses to end-stage renal disease. Overall less than 50 cases have been reported in the lite...

    Authors: Monica Sivakumar, Balan Louis Gaspar and Balakrishnan Narasimhan
    Citation: Surgical and Experimental Pathology 2021 4:8
  33. Extracellular matrix (ECM) represents more than a mere intercellular cement. It is physiologically active in cell communication, adhesion and proliferation. Collagen is the most abundant protein, making up to ...

    Authors: Rodrigo de Andrade Natal, Javier Adur, Carlos Lenz Cesar and José Vassallo
    Citation: Surgical and Experimental Pathology 2021 4:7
  34. A solitary fibrous tumor (SFT) is an uncommon neoplasm of mesenchymal and probably fibroblastic origin, occurring mainly in the extremities, and pleura. However, a primary involvement of endocrine organs is ra...

    Authors: S. E. Huisman, I. Verlinden, P. van Battum and J. W. A. Leijtens
    Citation: Surgical and Experimental Pathology 2021 4:6
  35. Adenomatoid tumors (AT) are benign neoplasms of mesothelial origin that occur more frequently in the genital tracts. In uterus, AT are usually located in the subserosa of the cornual myometrium. Microscopicall...

    Authors: Flora Ávila Adorno, Karina Munhoz de Paula Alves Coelho, Giuliano Stefanello Bublitz, Jaqueline Stall and Paulo Henrique Condeixa de França
    Citation: Surgical and Experimental Pathology 2021 4:5
  36. Classification of renal cell carcinomas has become more challenging. The 2016 WHO classification included 14 different subtypes and 4 emerging/provisional entities, and recent literature indicates new entities...

    Authors: Daniel Abensur Athanazio, Luciana Schultz Amorim, Isabela Werneck da Cunha, Katia Ramos Moreira Leite, Alexandre Rolim da Paz, Regina de Paula Xavier Gomes, Fabio Rocha Fernandes Tavora, Sheila Friedrich Faraj, Marcela Santos Cavalcanti and Stephania Martins Bezerra
    Citation: Surgical and Experimental Pathology 2021 4:4
  37. Muscle biopsies are important diagnostic procedures in neuromuscular practice. Recent advances in genetic analysis have profoundly modified Myopathology diagnosis.

    Authors: Ana Cotta, Elmano Carvalho, Antonio Lopes da-Cunha-Júnior, Jaquelin Valicek, Monica M. Navarro, Sidney Baptista Junior, Eni Braga da Silveira, Maria Isabel Lima, Bruno Arrivabene Cordeiro, Alexandre Faleiros Cauhi, Miriam Melo Menezes, Simone Vilela Nunes, Antonio Pedro Vargas, Rafael Xavier Neto and Julia Filardi Paim
    Citation: Surgical and Experimental Pathology 2021 4:3
  38. Complete lymph node dissection (CLND) following a positive sentinel lymph node biopsy (SLNB) has been the standard treatment for years. However, there is increasing evidence that CLND could be omitted. Approxi...

    Authors: Maribel L. Da Cunha Cosme, Juan F. Liuzzi Samaterra, Saul A. Siso Cardenas and José I. Chaviano Hernández
    Citation: Surgical and Experimental Pathology 2021 4:2
  39. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Mitul B. Modi, Ata S. Moshiri, Toru Shoji, Martin C. Mihm Jr, Xiaowei Xu and David E. Elder
    Citation: Surgical and Experimental Pathology 2021 4:1

    The original article was published in Surgical and Experimental Pathology 2020 3:16

  40. The IgG4-related disease (IgG4-RD) is a systemic immune-mediated non-neoplastic disease associated with IgG4 positive plasma cells and fibrosis that often presents as a mass lesion. Although the disease could ...

    Authors: Balan Louis Gaspar
    Citation: Surgical and Experimental Pathology 2020 3:30
  41. Breast cancer is a major public health problem worldwide. It is recommended that small breast lesions or those suspicious for malignancy be evaluated via histopathological examination (“core biopsy” or surgica...

    Authors: Jessica Aline Tomelin de Cursi, Mariângela Esther Alencar Marques, Cristina Andrea Campos de Assis Cunha Castro, Fernando Carlos Schmitt and Cleverson Teixeira Soares
    Citation: Surgical and Experimental Pathology 2020 3:29

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