Table 1 Morphological differential diagnosis of Sclerosing Epithelioid Fibrosarcoma
From: Sclerosing epithelioid fibrosarcoma – a rare variant with myriads of differentials
Morphological Differential diagnosis | Immunohistochemical distinguishing markers |
|---|---|
Sclerosing epithelioid fibrosarcoma | MUC-4 ( +) |
Ossifying fibromyxoid tumour | CD10 ( +), S-100 ( +) |
Sclerosing Rhabdomyosarcoma | MyoD1 (Strong), Myogenin |
Metastatic carcinoma | Cytokeratin expression |
Low grade fibromyxoid sarcoma | Morphological clue is enough for definitive diagnosis |
Osteosarcoma | SATB2 ( +) |
Epithelioid hamenagioendothelioma | Cytokeratins and CAMTA1 ( +) |