Fig. 1

Cytological and histopathological photomicrographs of the metastatic and primary tumor

a, b) May Grunwald-Giemsa and Papanicolaou stained smears show clusters of plasmacytoid cells with eccentric nuclei and scant to moderate cytoplasm. [200x magnification]

c-f) Immunocytochemistry in cell block preparation shows positive expression for Melan-A (c), HMB-45 (d), S-100 (e) and negative expression for ER (f). [200x magnification]

g-h) Hematoxylin and eosin-stained sections show a submucosal tumor comprising of tumor cells arranged in nests. Individual tumor cells were epithelioid in shape, with high nucleus to cytoplasmic ratio and scant to moderate cytoplasm with high mitotic activity. [100x, 200x magnification]

i) Immunohistochemistry shows positive expression of HMB-45 in the tumor cells. [200x magnification]