Table 1 Articles presenting cases of multiple adenomatoid tumors of the uterus
From: Re-thinking uterine fibroids in immunocompromised patients: adenomatoid tumors
Year | Authors | Age | Gynecological antecedents | Commorbidities | Immunodeficiency | AUB | Type of treatment | Number | Size (largest diameter; cm) | Location | Histopathological variant | Positive IHC markers | Negative IHC markers |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2022 | case | 34 | pain | SLE, CKD | yes | yes | hysterectomy | 4 | 4.5 | SS, IM | adenoid + angiomatoid | CK, CR, D2-40 | actin |
2021 | Hafiz B et al. | 35 | pain | no data | no | yes | enucleation | multiple | 9 | unknown | adenoid | D2-40, CK7 | CD31, CK20 |
2021 | Lerias S et al. | 4 out of 6 | ESRD | 2 out of 6 | |||||||||
median 45 | no data | no data | yes | hysterectomy | multiple | IM | cystic + angiomatoid | no data | no data | ||||
median 45 | no data | no data | yes | hysterectomy | multiple | 4.5 | IM | cystic + angiomatoid | no data | no data | |||
median 45 | no data | no data | yes | hysterectomy | multiple | 3 | SM | cystic + angiomatoid | no data | no data | |||
median 45 | no data | no data | yes | hysterectomy | multiple | 1.5 | IM, SS | cystic + angiomatoid | no data | no data | |||
2018 | Goode et al. | 1 out of 15 | |||||||||||
60 | AToU | IHD;SOT | yes | no | hysterectomy | 3 | 6 | IM | no data | no data | no data | ||
2018 | Tamura et al. | 6 out of 14 | |||||||||||
46 | endometrial cancer | cytotoxic treatment | no | no | hysterectomy | multiple | 50mm2 | no data | no data | CK, D2-40, p16 | no data | ||
39 | endometrial cancer | cytotoxic treatment | no | no | hysterectomy | multiple | 473mm2 | no data | no data | CK, D2-40, p16 | no data | ||
38 | endometrial cancer | SLE | yes | no | hysterectomy | multiple | 90mm2 | no data | no data | CK, D2-40, p16 | no data | ||
41 | leiomyoma | SOT | yes | no | hysterectomy | multiple | 85mm2 | no data | no data | CK, D2-40, p16 | no data | ||
44 | leiomyoma | SLE | yes | no | hysterectomy | multiple | 550 mm2 | no data | angiomatoid | CK, D2-40, p16 | no data | ||
55 | none | MAGIC syndrome | yes | no | hysterectomy | multiple | 10mm2 | no data | no data | CK, D2-40, p16 | no data | ||
2017 | Chen HF et al. | 4 out of 102 | |||||||||||
mean 39.3 | menstrual disorder | no data | no data | yes | n/a | multiple | average 2.3 | IM, SS | adenoid + angiomatoid | HBME-1, CR, D2-40 CK | CEA | ||
2014 | Nakayama H et al. | 1 out of 10 | |||||||||||
36 | no data | no data | no | no data | enucleation | 2 | 1 | no data | no data | no data | no data | ||
2015 | Ranjan et al. | 1 out of 5 | |||||||||||
36 | menstrual disorder | no data | no | yes | hysterectomy | mutliple | 3 | IM | cystic | no data | no data | ||
2010 | Kalidindi & Odejinmi | 1out of 2 | |||||||||||
39 | infertility | none | no | yes | enucleation | 2 | 7 | IM | adenoid + angiomatoid | CAM5.2 | no data | ||
2008 | Duval H et al. | 43 | leiomyoma | SOT | yes | yes | hysterectomy | 3 | 3 | IM | adenoid | AE1/AE3, CR, HMBE1 | no data |
2007 | Saran M et al. | 34 | infertility | none | no | yes | enucleation | 2 | 10 | SS | cystic | CR, CK5/6 | CD31, CD34, BerEP4, CEA |
2005 | Amre R et al. | 52 | menstrual disorder | degenerative diseases | no | yes | hysterectomy | 3 | 1.5 | SS,IM | solid | AE1/AE3 | no data |
2003 | Cserni G et al. | 41 | menstrual disorder | IgA nephropathy | yes | yes | hysterectomy | diffuse | 2 | IM | adenoid + angiomatoid | CK | no data |
2003 | Cheng & Wee | 34 | painless abdominal mass | IgA nephropathy, SOT | yes | yes | hysterectomy | diffuse | 3 | IM | adenoid + angiomatoid | AE1/3, HBME-1, CR, focal thrombomodulin, vimentin | CD34 |
2001 | Nogales FF et al. | 1 out of 50 | |||||||||||
mean 45 | menstrual disorder | no data | no data | yes | hysterectomy | 2 | 2.1 | SS | adenoid + angiomatoid | CAM5.2, CR, HMBE1 | ER; PR, EMA, inhibin | ||
2000 | Luchs J et al. | 25 | menstrual disorder | no data | no data | yes | hysterectomy | multiple | IM | no data | no data | no data | |
2000 | Bülent Tiras et al. | 34 | menstrual disorder | chronic glomerulonephritis; SOT | yes | yes | enucleation | 8 | 5 | IM, SS | cystic | CK | factor VIII |
1998 | Di Stefano et al. | 30 | menstrual disorder | none | no data | yes | enucleation | 3 | 4.5 | IM | adenoid + angiomatoid | HMBE1,CK; focal EMA, vimetin | Ber-EP4, factor VIII, CEA, CD15 |
1992 | Livingston et al. | 39 | menstrual disorder | SLE, SOT | yes | yes | hysterectomy | 3 | 4 | SS | cystic | CK | factor VIII |
1988 | Srigley & Colgan | 45 | menstrual disorder | HTN | no | yes | hysterectomy | multiple | 3 | IM, SS, SM | angiomatoid + cystic | CK | factor VIII, EMA |
1984 | Konishi & Fujii | 39 | menstrual disorder | none | no | yes | hysterectomy | multiple | no data | IM | adenoid | no data | no data |
1980 | Tiltman AJ | 2 of 12 | |||||||||||
47 | menstrual disorder | no data | no data | no data | hysterectomy | 2 | 3 | IM, SS | adenoid | no data | no data | ||
47 | menstrual disorder | no data | no data | no data | hysterectomy | 2 | 0.8 | IM, SS | adenoid | no data | no data | ||
1967 | Young & Taylor | 1 of 14 | |||||||||||
median 42 | none | no data | no data | no | hysterectomy | 2 | 0.7–7.5 cm | SS | adenoid + angiomatoid | no data | no data |