Younger than 18 years (n = 46) | 18 years or older (n = 74) | p-value* | |||
---|---|---|---|---|---|
n | % | n | % | ||
Global hyperplasia | 6 | 13.0 | 36 | 48.6 | < 0.001 |
Megaloblasts | 11 | 23.9 | 27 | 36.5 | 0.107 |
Eosinophilia | 4 | 8.7 | 8 | 10.8 | 0.483 |
Lymphocytosis | 12 | 26.1 | 15 | 20.3 | 0.300 |
Lymphoid aggregate | 1 | 2.2 | 6 | 8.1 | 0.174 |
Plasmacytosis | 12 | 26.1 | 25 | 33.8 | 0.248 |
Megakaryocytic series | |||||
Hypercellularity | 39 | 84.8 | 70 | 94.6 | 0.070 |
Lobulated nucleus | 13 | 28.3 | 22 | 29.7 | 0.516 |
Micromegakaryocytes | 13 | 28.3 | 33 | 44.6 | 0.054 |
Grouping | 22 | 47.8 | 40 | 54.1 | 0.317 |
Nuclear fragmentation | 16 | 34.8 | 28 | 37.8 | 0.455 |
Nuclear hyperchromasia | 11 | 23.9 | 15 | 20.3 | 0.400 |
Moderate/severe dysplasia | 24 | 52.2 | 51 | 68.9 | 0.050 |
Reticulin Grade 2/3 | 1 | 2.2 | 8 | 10.8 | 0.077 |
Positive hemosiderin | 4 | 8.7 | 20 | 27.0 | 0.011 |