Skip to main content

Table 3 Association between BM morphological parameters and age group in 120 patients with ITP

From: Impact of reticulin stain in clinical outcome of Immune Thrombocytopenic Purpura (ITP): a pathologist perspective

 

Younger than 18 years

(n = 46)

18 years or older

(n = 74)

p-value*

n

%

n

%

Global hyperplasia

6

13.0

36

48.6

 < 0.001

Megaloblasts

11

23.9

27

36.5

0.107

Eosinophilia

4

8.7

8

10.8

0.483

Lymphocytosis

12

26.1

15

20.3

0.300

Lymphoid aggregate

1

2.2

6

8.1

0.174

Plasmacytosis

12

26.1

25

33.8

0.248

Megakaryocytic series

 Hypercellularity

39

84.8

70

94.6

0.070

 Lobulated nucleus

13

28.3

22

29.7

0.516

 Micromegakaryocytes

13

28.3

33

44.6

0.054

 Grouping

22

47.8

40

54.1

0.317

 Nuclear fragmentation

16

34.8

28

37.8

0.455

 Nuclear hyperchromasia

11

23.9

15

20.3

0.400

 Moderate/severe dysplasia

24

52.2

51

68.9

0.050

Reticulin Grade 2/3

1

2.2

8

10.8

0.077

Positive hemosiderin

4

8.7

20

27.0

0.011

  1. *Statistical tests used: Chi-square and Fisher exact