Table 2 Genotypes for TGFB1 and TGFBR2 of BC patients
SNP | Total (n = 34) | LB-HER2+ (n = 9) | HER2 (n = 9) | TN (n = 16) |
|---|---|---|---|---|
TGFBR2 G-875A | ||||
GG | 17 (50.0) | 4 (44.4) | 2 (22.2) | 11 (68.8) |
GA | 15 (44.1) | 4 (44.4) | 7 (77.8) | 4 (25.0) |
AA | 2 (5.9) | 1 (11.1) | 0 (0.0) | 1 (6.3) |
TGFB1 G-800A | ||||
GG | 31 (91.2) | 8 (88.9) | 9 (100.0) | 14 (87.5) |
GA | 3 (8.8) | 1 (11.1) | 0 (0.0) | 2 (12.5) |
AA | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
TGFB1 C-509T | ||||
CC | 6 (17.6) | 2 (22.2) | 3 (33.3) | 1 (6.3) |
CT | 20 (58.8) | 5 (55.6) | 4 (44.4) | 11 (68.8) |
TT | 8 (23.5) | 2 (22.2) | 2 (22.2) | 4 (25.0) |
TGFB1 T29C | ||||
TT | 5 (14.7) | 3 (33.3) | 1 (11.1) | 1 (6.3) |
TC | 18 (52.9) | 5 (55.6) | 4 (44.4) | 9 (56.3) |
CC | 11 (32.4) | 1 (11.1) | 4 (44.4) | 6 (37.5) |
TGFB1 G74C | ||||
GG | 28 (82.4) | 8 (88.9) | 6 (66.7) | 14 (87.5) |
GC | 4 (11.8) | 1 (11.1) | 1 (11.1) | 2 (12.5) |
CC | 2 (5.9) | 0 (0.0) | 2 (22.2) | 0 (0.0) |