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Table 3 Agreement between P53 and Ki-67 tests with anatomopathological results of borderline/malignant PT

From: Accuracy of p53 and ki-67 in the graduation of phyllodes tumor, a model for practical application

Diagnostic properties

P53

Ki-67

P53 or Ki-67a

P53 & Ki-67b

% (95% CI)

% (95% CI)

% (95% CI)

% (95% CI)

Sensitivity

63.9 (46.2–79.2)

88.9 (73.9–96.9)

100 (90.3–100)

52.8 (35.5–69.6)

Specificity

95.5 (90.2–98.3)

96.4 (90.9–99)

91.8 (85–96.2)

100 (96.7–100)

Positive predictive value

82.1 (63.1–93.9)

88.9 (73.9–96.9)

80 (65.4–90.4)

100 (82.4–100)

Negative predictive value

88.9 (81.9–94)

96.4 (90.9–99)

100 (96.4–100)

86.6 (79.4–92)

Accuracy

87.7 (81.2–92.5)

94.5 (89.5–97.6)

93.8 (88.6–97.1)

88.4 (82–93.1)

Kappa

0.64

0.85

0.85

0.63

P

< 0.001

< 0.001

< 0.001

< 0.001

  1. CI confidence interval
  2. aPositive for any test
  3. bPositive for both tests