From: Accuracy of p53 and ki-67 in the graduation of phyllodes tumor, a model for practical application
Diagnostic properties | P53 | Ki-67 | P53 or Ki-67a | P53 & Ki-67b |
---|---|---|---|---|
% (95% CI) | % (95% CI) | % (95% CI) | % (95% CI) | |
Sensitivity | 63.9 (46.2–79.2) | 88.9 (73.9–96.9) | 100 (90.3–100) | 52.8 (35.5–69.6) |
Specificity | 95.5 (90.2–98.3) | 96.4 (90.9–99) | 91.8 (85–96.2) | 100 (96.7–100) |
Positive predictive value | 82.1 (63.1–93.9) | 88.9 (73.9–96.9) | 80 (65.4–90.4) | 100 (82.4–100) |
Negative predictive value | 88.9 (81.9–94) | 96.4 (90.9–99) | 100 (96.4–100) | 86.6 (79.4–92) |
Accuracy | 87.7 (81.2–92.5) | 94.5 (89.5–97.6) | 93.8 (88.6–97.1) | 88.4 (82–93.1) |
Kappa | 0.64 | 0.85 | 0.85 | 0.63 |
P | < 0.001 | < 0.001 | < 0.001 | < 0.001 |