Fig. 6

Ultrastructural evaluation. a. almost normal ultrastructural morphologic pattern. b. nemaline rods are rod shaped structures (arrows), c. lattice structure similar to Z disks in nemaline bodies in a patient with nemaline congenital myopathy. d. abnormal mitochondrial accumulation with paracrystalline inclusions (arrow) in patient with mitochondriopathy subtype progressive external ophthalmoplegia. e. tubulorreticular inclusions (arrow) inside vessel wall endothelial cell cytoplasm in patient with dermatomyositis. f. 15 to 18 nm filamentous inclusion (arrow) in patient with sporadic inclusion body myositis. g. area of myofibrillar disorganization (arrow) with few mitochondria (core) in central core congenital myopathy. h. electrondense amorphous deposit (arrow) in patient with myofibrillar myopathy. i. elongated electrondense masses (arrows) in patient with myofibrillar myopathy. (Transmission electron microscopy a. 2500x, b. 2500x, c. 150,000x, d. 25,000x, e. 15,000x, f. 20,000x, g. 2500x, h. 30,000x, i. 5000x)