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Table 4 “Double- expressor” lymphomas and clinical evolution, according to the BCL2 cut-off adopted in the IHC (50% or 70%)

From: 50% versus 70%: is there a difference between these BCL2 cut-offs in immunohistochemistry for diffuse large B-cell lymphomas (DLBCL)?

 

> 50% (N = 27)

p-value*

> 70% (N = 22)

p-value*

Non-germinal center-like

14 (51.8%)

0.575

10 (45.4%)

0.298

Stage III/IV

13 (48.1%)

0.266

11 (50%)

0.206

BMa

3 (11.1%)

0.224

3 (13.6%)

0.432

CNSb

2 (7.4%)

0.566

2 (9.0%)

0.426

Deathc

7 (28%)

0.030

6/20 (30%)

0.099

  1. *Chi-square and Fisher’s exact test; p < 0.05
  2. aBM Bone marrow infiltration
  3. bCNS Central nervous system infiltration
  4. cConsidering a period of 5 years after the diagnosis