Table 3 Features Combined features of some chronic autoimmune diseases
From: Fibrosing pneumonia – how to diagnose, and how to recognize the etiology?
RhA: UIP pattern, LIP pattern, histiocytic or epitheloid cell granulomas, hyperplasia of BALT, amyloid deposition, mixed lymphocytes positive for CD4, CD8, and CD20. This will also help to exclude HP, which will present with predominant CD8+ cells. Rare or absent FOXP3 regulatory Tcells (Figs. 15 and 16). | |
SSc: UIP pattern, LIP pattern, no granulomas, hyperplasia of BALT, amyloid or immune complex deposition (Fig. 17) | |
SLE: hemorrhage, infarcts, immune complex deposits, NSIP or LIP pattern, OP (Fig. 18) | |
DMM: UIP pattern, NSIP pattern, granulomas (Fig. 19) |