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Table 5 Univariate model for analysis of the immunohistochemical expression according a binary category (absent/low vs high expression) for each VEGF subunit and receptors in GBMs

From: The immunohistochemical landscape of the VEGF family and its receptors in glioblastomas

  Category N (%) Median OS (CI 95%)* HR (CI 95%) P
VEGF-A (62) Absent/Low 5 (8.1) 4.77 (2.63; −) 1   
High expression 57 (91.9) 6.43 (4.69; 12.90) 0.84 (0.30–2.35) 0.74
VEGF-C (56) Absent/Low 3 (5.4) 6.22 (2.04; −) 1   
High expression 53 (94.6) 5.72 (4.01; 12.70) 1.15 (0.35–3.72) 0.82
VEGF-D (63) Absent/Low 8 (12.7) 10.08 (3.52; −) 1   
High expression 55 (87.3) 6.02 (4.64; 12.70) 1.22 (0.52–2.88) 0.64
VEGFR-1 (66) Absent/Low 1 (1.5) 14.97 (−; −) 1   
High expression 65 (98.5) 6.66 (5.20; 12.80) 1.19 (0.16–8.64) 0.87
VEGFR-2 (64) Absent/Low 1 (1.6) 14.97 (−; −) 1   
High expression 63 (98.4) 6.02 (4.64; 12.80) 1.25 (0.17–9.10) 0.83
VEGFR-3 (50) Absent/Low 1 (2) 14.97 (−; −) 1   
High expression 49 (98) 5.89 (4.57; 14.10) 1.12 (0.15–8.27) 0.91