Table 5 Univariate model for analysis of the immunohistochemical expression according a binary category (absent/low vs high expression) for each VEGF subunit and receptors in GBMs
From: The immunohistochemical landscape of the VEGF family and its receptors in glioblastomas
Category | N (%) | Median OS (CI 95%)* | HR | (CI 95%) | P | |
|---|---|---|---|---|---|---|
VEGF-A (62) | Absent/Low | 5 (8.1) | 4.77 (2.63; −) | 1 | ||
High expression | 57 (91.9) | 6.43 (4.69; 12.90) | 0.84 | (0.30–2.35) | 0.74 | |
VEGF-C (56) | Absent/Low | 3 (5.4) | 6.22 (2.04; −) | 1 | ||
High expression | 53 (94.6) | 5.72 (4.01; 12.70) | 1.15 | (0.35–3.72) | 0.82 | |
VEGF-D (63) | Absent/Low | 8 (12.7) | 10.08 (3.52; −) | 1 | ||
High expression | 55 (87.3) | 6.02 (4.64; 12.70) | 1.22 | (0.52–2.88) | 0.64 | |
VEGFR-1 (66) | Absent/Low | 1 (1.5) | 14.97 (−; −) | 1 | ||
High expression | 65 (98.5) | 6.66 (5.20; 12.80) | 1.19 | (0.16–8.64) | 0.87 | |
VEGFR-2 (64) | Absent/Low | 1 (1.6) | 14.97 (−; −) | 1 | ||
High expression | 63 (98.4) | 6.02 (4.64; 12.80) | 1.25 | (0.17–9.10) | 0.83 | |
VEGFR-3 (50) | Absent/Low | 1 (2) | 14.97 (−; −) | 1 | ||
High expression | 49 (98) | 5.89 (4.57; 14.10) | 1.12 | (0.15–8.27) | 0.91 |