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Fig. 4 | Surgical and Experimental Pathology

Fig. 4

From: Neoplastic cells parasitized by Mycobacterium leprae: report of two cases of melanocytic nevus and one of basal cell carcinoma

Fig. 4

Parasitism of basal cell carcinoma by M. leprae in case 3. Sequential sections stained with hematoxylin-eosin (HE) (a) and immunohistochemistry (IHC) (b and c). a Basal cell carcinoma (→) and adjacent leprosy lesion (*) are observed. b IHC anti-cytokeratin (34ßE12) immunostaining highlighting basal cell carcinoma (→) and negative leprosy lesion (*). Sequential sections stained by HE (d), Fite-Faraco (FF) (e), and IHC (f). d Left: lepromatous lesion (*); right: basal cell carcinoma (→). e Bacilloscopy of the histological sections (FF) shows numerous bacilli inside the macrophages (*) and in vacuoles of basal cell carcinoma cells (→). f and h Positive double staining (IHC-34ßE12 and FF) for basal cell carcinoma (→) and negative for the leprosy lesion macrophages (*), both containing bacilli in the cytoplasm. g FF staining showing large numbers of bacilli in intracytoplasmic vacuoles of basaloid cells and also in areas of formation of horny pseudocysts (→)

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Surgical and Experimental Pathology

ISSN: 2520-8454

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