Table 5 Mean p16 expression (mean H-score) and complete loss of p16 expression in urothelial carcinoma
From: Prognostic significance of p16 immunohistochemical expression in urothelial carcinoma
Clinicopathologic features | Mean ± SD | P-Value | Complete Loss of p16 expression n (%) |
|---|---|---|---|
Overall | 64.61 ± 93.13 | 33 (27.3) | |
Gender | |||
Male | 64.23 ± 92.46 | 0.942 | 23 (19) |
Female | 65.63 ± 96.34 | 10 (8.26) | |
Age group | |||
26–50 years | 59.34 ± 73.78 | 0.707 | 5 (4.13) |
> 50 years | 66.87 ± 99.13 | 28 (23.14) | |
Tumor grade | |||
Low grade | 26.93 ± 38.96 | 0.000 | 18 (14.87) |
High grade | 105.55 ± 115.48 | 15 (12.39) | |
Muscularis propria Invasiona | |||
Can’t assessed | 46.97 ± 77.86 | 0.000 | 14 (11.57) |
Present | 156.80 ± 124.37 | 4 (3.30) | |
Absent | 43.96 ± 68.23 | 15 (12.39) | |
Lamina propria Invasion | |||
Present | 131.30 ± 120.79 | 0.000 | 8 (6.61) |
Absent | 39.61 ± 65.40 | 25 (20.66) | |
Recurrence (n = 54) | |||
Yes | 85.21 ± 107.69 | 0.287 | 4 (3.30) |
No | 56.29 ± 89.59 | 8 (6.61) | |
Survival Status (n = 54) | |||
Alive | 51.33 ± 85.37 | 0.003 | 12 (9.91) |
Died of disease | 155.00 ± 114.94 | 0 (0) | |