Fig 1.
Human mammary glands with immunostaining for CaV1.1, CaV1.2 and CaV1.3. Identified by DAB chromogen and counterstained with hematoxylin. 600x magnification. A-C mammary lobes without histological alterations. D-F ductal regions with three or more layers of epithelial cells above the basal membrane and presence of a ductal region without alteration in F (×). G-I epithelial cell proliferation forming intraductal projections or solid masses restricted to the terminal ductal lobular units with an inflammatory infiltrate associated in G (*). J-L atypical epithelial proliferation, creating isolated cell nests in the mammary stroma