Impact of reticulin stain in clinical outcome of Immune Thrombocytopenic Purpura (ITP): a pathologist perspective

Table 4 Association between clinical parameters and age group in 120 patients with ITP

	Younger than 18 years (n = 46)		18 years or older (n = 74)		p-value^*
	n	%	n	%	p-value^*
Petechiae	30	65,2	50	67,6	0,471
Ecchymosis	39	84,8	55	74,3	0,130
Hematoma	7	15,2	18	24,3	0,168
Epistaxis	15	32,6	27	36,5	0,408
Purpura	11	23,9	16	21,6	0,469
Oral bleeding	25	54,3	36	48,6	0,338
Mucosal bleeding	17	37,0	37	50,0	0,113
Internal bleeding^b	3	6,5	13	17,6	0,069
Anemia	9	19,6	15	20,3	0,560
Leukopenia	0	0,0	1	1,4	0,617
Lymphopenia	11	23,9	8	10,8	0,050
Thrombocytopenia	44	95,7	68	91,9	0,345
Infection	21	45,7	6	8,1	< 0,001
Splenomegaly	3	6,5	2	2,7	0,286
Use of systemic medication	2	4,3	30	40,5	< 0,001
Systemic arterial hypertension	1	2,2	26	35,1	< 0,001
Diabetes mellitus	0	0,0	8	10,8	0,018
Dyslipidemia	0	0,0	11	14,9	0,004
Obesity	1	2,2	9	12,2	0,050
Smoking	0	0,0	13	17,6	0,001
Past autoimmune disease	0	0,0	5	6,8	0,085
Hypothyroidism	0	0,0	6	8,1	0,051
Viral hepatitis	0	0,0	9	12,2	0,011
H. pylori gastritis	1	2,1	7	9,4	0,800

^*Statistical tests used: Chi-square and Fisher exact. ^b Hemorrhages of the gastrointestinal tract, respiratory tract or central nervous system