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Table 4 Association between clinical parameters and age group in 120 patients with ITP

From: Impact of reticulin stain in clinical outcome of Immune Thrombocytopenic Purpura (ITP): a pathologist perspective

  Younger than 18 years
(n = 46)
18 years or older
(n = 74)
p-value*
n % n %
Petechiae 30 65,2 50 67,6 0,471
Ecchymosis 39 84,8 55 74,3 0,130
Hematoma 7 15,2 18 24,3 0,168
Epistaxis 15 32,6 27 36,5 0,408
Purpura 11 23,9 16 21,6 0,469
Oral bleeding 25 54,3 36 48,6 0,338
Mucosal bleeding 17 37,0 37 50,0 0,113
Internal bleedingb 3 6,5 13 17,6 0,069
Anemia 9 19,6 15 20,3 0,560
Leukopenia 0 0,0 1 1,4 0,617
Lymphopenia 11 23,9 8 10,8 0,050
Thrombocytopenia 44 95,7 68 91,9 0,345
Infection 21 45,7 6 8,1  < 0,001
Splenomegaly 3 6,5 2 2,7 0,286
Use of systemic medication 2 4,3 30 40,5  < 0,001
Systemic arterial hypertension 1 2,2 26 35,1  < 0,001
Diabetes mellitus 0 0,0 8 10,8 0,018
Dyslipidemia 0 0,0 11 14,9 0,004
Obesity 1 2,2 9 12,2 0,050
Smoking 0 0,0 13 17,6 0,001
Past autoimmune disease 0 0,0 5 6,8 0,085
Hypothyroidism 0 0,0 6 8,1 0,051
Viral hepatitis 0 0,0 9 12,2 0,011
H. pylori gastritis 1 2,1 7 9,4 0,800
  1. *Statistical tests used: Chi-square and Fisher exact. b Hemorrhages of the gastrointestinal tract, respiratory tract or central nervous system