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Table 1 Reported cases of rhabdomyosarcoma of bone in the literature including treatment and outcomes

From: Upfront surgical resection for primary bone tumors: rationale and potential benefits

Author

Year

Cases

Age/Sex

Location

Diagnosis

Treatment

Outcome

Lamovec et al

1994

1

31/M

Tibia, proximal

Pleomorphic rhabdomyosarcoma of bone

Above knee amputation with postoperative chemotherapy

Died of Metastatic disease at 3 years 4 months

Hsueh et al

1986

1

11/M

Femur, distal

Embryonal rhabdomyosarcoma of bone

Hip disarticulation, adjuvant chemotherapy

Lung metastases - lost to follow-up

Pasquel et al

1976

1

13/F

Femur, diaphysis

Embryonal rhabdomyosarcoma of bone

Initially refused radical surgery – radiotherapy and chemotherapy with no improvement, coxofemoral disarticulation

Lung metastases

Thomas et al

2002

1

22/M

Humerus, proximal

Embryonal rhabdomyosarcoma of bone

Neoadjuvant chemotherapy with forequarter amputation

Lost to follow-up, died 11 months post-operatively

Lucas et al

1996

1

7/F

Femur, diaphysis

Embryonal rhabdomyosarcoma of bone

Neoadjuvant chemotherapy, above knee amputation, postop radiation

No signs of local recurrence/metastasis 7 months post op

Oda et al

1993

1

32/M

Ilium, wing

Embryonal rhabdomyosarcoma of bone

Hemipelvectomy with adjuvant chemotherapy

No signs of local recurrence/metastasis 4 years post op

Balogh et al

2016

2

17/M

9/M

Pelvis, diffusely

Pelvis, diffusely

Alveolar rhabdomyosarcoma of bone in both cases

Chemotherapy alone

Died at 7 months

Died at 30 months

Hakozaki et al

2007

1

16/F

Sacrum

Embryonal rhabdomyosarcoma of bone

Chemotherapy and radiation

Died at 17 months

Wang et al

1999

1

45/M

Femur, proximal

Pleomorphic rhabdomyosarcoma of bone

Neoadjuvant chemotherapy, limb salvage surgery, adjuvant chemotherapy

No signs of local recurrence/metastasis 4 years post op

Bressner et al

2016

1

34/M

Femur, distal

Pleomorphic rhabdomyosarcoma of bone

Neoadjuvant chemotherapy (presumed Ewing), rotationplasty, adjuvant chemotherapy

Died at 8 months

This Study

2019

1

39/M

Femur, distal

Pleomorphic rhabdomyosarcoma of bone

Limb salvage surgery with adjuvant chemotherapy

No signs of local recurrence 2 years postop