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Table 1 Reported cases of rhabdomyosarcoma of bone in the literature including treatment and outcomes

From: Upfront surgical resection for primary bone tumors: rationale and potential benefits

AuthorYearCasesAge/SexLocationDiagnosisTreatmentOutcome
Lamovec et al1994131/MTibia, proximalPleomorphic rhabdomyosarcoma of boneAbove knee amputation with postoperative chemotherapyDied of Metastatic disease at 3 years 4 months
Hsueh et al1986111/MFemur, distalEmbryonal rhabdomyosarcoma of boneHip disarticulation, adjuvant chemotherapyLung metastases - lost to follow-up
Pasquel et al1976113/FFemur, diaphysisEmbryonal rhabdomyosarcoma of boneInitially refused radical surgery – radiotherapy and chemotherapy with no improvement, coxofemoral disarticulationLung metastases
Thomas et al2002122/MHumerus, proximalEmbryonal rhabdomyosarcoma of boneNeoadjuvant chemotherapy with forequarter amputationLost to follow-up, died 11 months post-operatively
Lucas et al199617/FFemur, diaphysisEmbryonal rhabdomyosarcoma of boneNeoadjuvant chemotherapy, above knee amputation, postop radiationNo signs of local recurrence/metastasis 7 months post op
Oda et al1993132/MIlium, wingEmbryonal rhabdomyosarcoma of boneHemipelvectomy with adjuvant chemotherapyNo signs of local recurrence/metastasis 4 years post op
Balogh et al2016217/M
9/M
Pelvis, diffusely
Pelvis, diffusely
Alveolar rhabdomyosarcoma of bone in both casesChemotherapy aloneDied at 7 months
Died at 30 months
Hakozaki et al2007116/FSacrumEmbryonal rhabdomyosarcoma of boneChemotherapy and radiationDied at 17 months
Wang et al1999145/MFemur, proximalPleomorphic rhabdomyosarcoma of boneNeoadjuvant chemotherapy, limb salvage surgery, adjuvant chemotherapyNo signs of local recurrence/metastasis 4 years post op
Bressner et al2016134/MFemur, distalPleomorphic rhabdomyosarcoma of boneNeoadjuvant chemotherapy (presumed Ewing), rotationplasty, adjuvant chemotherapyDied at 8 months
This Study2019139/MFemur, distalPleomorphic rhabdomyosarcoma of boneLimb salvage surgery with adjuvant chemotherapyNo signs of local recurrence 2 years postop