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Fig. 2 | Surgical and Experimental Pathology

Fig. 2

From: Dealing with prostate cancer? Don’t let histiocytic lesions fool you!

Fig. 2

Case 2. Prostatic adenocarcinoma associated with malakoplakia. A high-grade adenocarcinoma with cribriform morphology merging a solid lesion (HE stain: a 40x and b 100x). Malakoplakia area shows dense histiocytic infiltrate intermixed with benign glands (c HE, 100x). Round basophilic inclusions are readily identified in HE stain within the cytoplasm of histiocytes (d HE, 400x). PAS stain in the transition zone highlights strong staining in malakoplakia (PAS – e 100x and f 400x). Round inclusions (Michaelis–Gutmann bodies) are strongly positive by von Kossa stain (von Kossa: g 100x and h 400x)

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