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Table 2 Etiology in UIP pattern

From: Fibrosing pneumonia – how to diagnose, and how to recognize the etiology?

 

Myofibroblastic foci, cystic remodeling, timely heterogeneity

LIP pattern ± hyperplasia of BALT

Organizing pneumonia pattern

DAD pattern

Granulomas or giant cells

Lymphocytes, subtypes?

IPF

present

no

no

± in exacerbation

no

No

Chronic autoimmune disease

present

Yes/no

Yes/no

no

Yes/no

Mixed CD4/8 and CD20 population

Chronic hypersensitivity pneumonia

present

Yes/no peribronchial lymphocyte aggregates

yes

no

yes

Predominant CD8 population