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Table 1 Histological features of the hepatocellular adenomas by histological classification

From: Relevance of morphological features for hepatocellular adenoma classification in pathology practice

Histological features

HHCA

n = 11

bHCA

n = 5

IHCA

n = 14

p value

steatosis mild

1(9.1%)

0

6(42.9%)

< 0.0001

steatosis moderate

3(27.3%)

0

3(21.4%)

steatosis severe

7(63.6%)

0

0

atypia

0

4(80%)

6(42.8%)

0.003

I. infiltrate mild

2(18.2%)

0

9(64.3%)

< 0.0001

I. infiltrate moderate

0

0

4(28.6%)

I. infiltrate severe

0

0

1(7.1%)

sinusoidal dilatation

0

0

14(100%)

< 0.0001

ductular reaction

0

0

10(71.4%)

< 0.0001

pseudoportal tracts

0

0

12(85.7%)

< 0.0001

fibrosis

2(18.2%)

0

3(21.4%)

0.82

  1. HHCA= hepatocellular adenoma with HNF1A mutation, bHCA= hepatocellular adenoma with beta catenin mutation, IHCA= inflammatory hepatocellular adenoma, I. infiltrate= inflammatory infiltrate. 0 = absent