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Table 6 Univariate and multivariate Cox regression analyses of different prognostic factors for disease-free survival (DFS) in PTC patients

From: Clinical, pathological and prognostic implications of USP22, SIRT1 and E-cadherin expression in papillary thyroid cancer (PTC) and adjacent non-neoplastic tissue

 

Univariate

Multivariate (stepwise)

HR

95.0% CI

P

HR

95.0% CI

P

Age < 40 vs >40Y

1.67

0.63–4.39

0.302

   

Sex M vs F

1.05

0.37–2.99

0.924

   

Histopathologicalsubtype

1.14

0.26–5.01

0.857

   

USP22, low vs. high

6.54

1.49–28.79

0.013

5.25

1.15–23.93

0.032

SIRT1, low vs. high

3.48

1.22–9.92

0.02

   

Ecadherin, low vs. high

0.29

0.08–1

0.05

   

LN involvement

3.31

1.22–9.01

0.019

   

Vascular invasion

3.69

1.06–12.9

0.041

   

Capsular invasion

4.03

1.52–10.67

0.005

   

Extra-thyroid extension

2.23

0.86–5.81

0.1

   

LN involvement

2.63

1.01–6.86

0.049

   

Stage

2.92

1.51–5.63

0.001

   

Distant metastasis

4.66

1.56–13.9

0.006

3.06

1.01–9.29

0.048

Surgery

1.14

0.65–2

0.641

   

Tumor size

3.21

1.17–8.78

0.023

   
  1. HR Hazard ratio, CI Confidence interval
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Surgical and Experimental Pathology

ISSN: 2520-8454

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