Fig. 8
From: Apc-related models of intestinal neoplasia: a brief review for pathologists
a Rectal prolapse in mice may mimic adenomatous change, as in humans. Here, note thickened hyperplastic reactive-appearing mucosa, with fibromuscular changes in the lamina propria. b In areas of prolapse, displacement of non-neoplastic crypts may mimic invasive adenocarcinoma. Here, a single herniated crypt is present in the submucosa. Note the rounded crypt profile and resemblance to the overlying crypts