Fig. 1

Hierarchical clustering of miRNAs according to tissue. In this heatmap, hierarchical data of miRNA expression profiling in LM, ULM, and LMS tumors are represented, with MM samples used as a normal reference. Blue coloring indicates miRNAs that are downregulated and red coloring indicates miRNAs that are upregulated. Type color bar indicates institutional origin of the LMS samples (purple: ACCC – A.C.Camargo Cancer Center; green: LIM58 – Hospital das Clinicas da Universidade de Sao Paulo) and histological classification of non-malignant tissues (LM - red color, LMA - blue and MM – ochre)