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Table 3 Association of Clinicopathologic features with survival status of the patients

From: Prognostic significance of p16 immunohistochemical expression in urothelial carcinoma

  n (%) P-Value
Alive (n = 45) Died of disease (n = 9) Total (n = 54)
Gender Male 35 (77.8) 7 (77.8) 42 (77.8) 1.000
Female 10 (22.2) 2 (22.2) 12 (22.2)
Age group ≤25 years 0 (0) 0 (0) 0 (0) 0.178
26–50 years 11 (24.4) 0 (0) 11 (20.4)
> 50 years 34 (75.6) 9 (100) 43 (79.6)
Tumor grade Low grade 27 (60) 2 (22.2) 29 (53.7) 0.065
High grade 18 (40) 7 (77.8) 25 (46.3)
Muscularis propria Invasion Can’t assessed 18 (40) 4 (44.4) 22 (40.7) 0.541
Present 5 (11.1) 2 (22.2) 7 (13)
Absent 22 (48.9) 3 (33.3) 25 (46.3)
Lamina propria Invasion Present 11 (24.4) 4 (44.4) 15 (27.8) 0.244
Absent 34 (75.6) 5 (55.6) 39 (72.2)
Recurrence Yes 14 (31.1) 9 (100) 23 (42.6) 0.000
No 31 (68.9) 0 (0) 31 (57.4)
P16 Expression Low expression 4 (8.9) 4 (44.4) 8 (14.8) 0.020
High expression 41 (91.1) 5 (55.6) 46 (85.2)
  1. Fisher Exact test was applied
  2. P-value≤0.05 considered as significant