Table 1 Association of p16 expression with Clinicopathologic features of Urothelial carcinoma
From: Prognostic significance of p16 immunohistochemical expression in urothelial carcinoma
n (%) | P-Value | ||||
|---|---|---|---|---|---|
Low Expression (n = 104) | High Expression (n = 17) | Total (n = 121) | |||
Gender | Male | 77 (74) | 11 (64.7) | 88 (72.7) | 0.557 |
Female | 27 (26) | 6 (35.3) | 33 (27.3) | ||
Age group | ≤25 years | 1 (1) | 0 (0) | 1 (0.8) | 0.346 |
26–50 years | 27 (26) | 2 (11.8) | 29 (24) | ||
> 50 years | 76 (73.1) | 15 (88.2) | 91 (75.2) | ||
Tumor gradea | Low grade | 62 (59.6) | 1 (5.9) | 63 (52.1) | 0.000 |
High grade | 42 (40.4) | 16 (94.1) | 58 (47.9) | ||
Muscularis propria Invasion | Can’t assessed | 39 (37.5) | 4 (23.5) | 43 (35.5) | 0.001 |
Present | 12 (11.5) | 9 (52.9) | 21 (17.4) | ||
Absent | 53 (51) | 4 (23.5) | 57 (47.1) | ||
Lamina propria Invasion | Present | 22 (21.2) | 11 (64.7) | 33 (27.3) | 0.001 |
Absent | 82 (78.8) | 6 (35.3) | 88 (72.7) | ||
Recurrence (n = 54) | Yes | 18 (39.1) | 5 (62.5) | 23 (42.6) | 0.264 |
No | 28 (60.9) | 3 (37.5) | 31 (57.4) | ||
Survival Status (n = 54) | Alive | 41 (89.1) | 4 (50) | 45 (83.3) | 0.020 |
Died of disease | 5 (10.9) | 4 (50) | 9 (16.7) | ||