Skip to main content

Table 1 Association of p16 expression with Clinicopathologic features of Urothelial carcinoma

From: Prognostic significance of p16 immunohistochemical expression in urothelial carcinoma

  n (%) P-Value
Low Expression (n = 104) High Expression (n = 17) Total (n = 121)
Gender Male 77 (74) 11 (64.7) 88 (72.7) 0.557
Female 27 (26) 6 (35.3) 33 (27.3)
Age group ≤25 years 1 (1) 0 (0) 1 (0.8) 0.346
26–50 years 27 (26) 2 (11.8) 29 (24)
> 50 years 76 (73.1) 15 (88.2) 91 (75.2)
Tumor gradea Low grade 62 (59.6) 1 (5.9) 63 (52.1) 0.000
High grade 42 (40.4) 16 (94.1) 58 (47.9)
Muscularis propria Invasion Can’t assessed 39 (37.5) 4 (23.5) 43 (35.5) 0.001
Present 12 (11.5) 9 (52.9) 21 (17.4)
Absent 53 (51) 4 (23.5) 57 (47.1)
Lamina propria Invasion Present 22 (21.2) 11 (64.7) 33 (27.3) 0.001
Absent 82 (78.8) 6 (35.3) 88 (72.7)
Recurrence (n = 54) Yes 18 (39.1) 5 (62.5) 23 (42.6) 0.264
No 28 (60.9) 3 (37.5) 31 (57.4)
Survival Status (n = 54) Alive 41 (89.1) 4 (50) 45 (83.3) 0.020
Died of disease 5 (10.9) 4 (50) 9 (16.7)
  1. Fisher Exact test was applied
  2. aChi-square test was applied
  3. P-value≤0.05 considered as significant